Necrotic Enteritis in Poultry

Necrotic enteritis (NE) is a common bacterial poultry disease, affecting approximately 40% of commercial broiler flocks and costing the industry up to an estimated $6 billion annually. Clinical outbreaks can cause mortality rates of up to 50%. In contrast, the subclinical form can lead to negative effects on growth rate and feed efficiency due to intestinal damage and impairment of nutrient absorption.  With feed being the highest input cost, poor conversion increases costs and reduces profitability.  Because of a lack of obvious symptoms, subclinical disease often remains untreated and continuously harms production.

The disease is commonly seen in broilers from around 2-6 weeks and is caused by the over-proliferation of Clostridium perfringens, with toxins damaging the gut and liver. Coccidia infection is often cited as a major predisposing factor, but poor feed quality and composition can also lead to the creation of a favourable environment for C. perfringens.  Cases of necrotic enteritis have been on the rise over recent years, the primary reason is thought to be a reduction in the use of antibiotics and ionophores.

The result is an increased demand for natural solutions to help build resilience and support birds during challenge periods, effectively creating a natural shield against disease. Orego-Stim contains 100% natural oregano essential oil (OEO) and has been shown to support broiler performance in previous coccidiosis and NE challenge studies, removing the risk of reduced performance and taking the gamble out of gut health.

What is Orego-Stim®?

Orego-Stim® is a high quality eubiotic containing an exclusive source of 100% natural oregano essential oil, with a unique and consistent fingerprint of active components produced to the highest quality standards. Natural oregano essential oil comprises of over 100 active compounds, most of which are phenolic compounds with varying antioxidant, antimicrobial and antifungal activity.

A Natural Solution to Support Necrotic Enteritis Management

All constituents present in natural oregano essential oil work together to help effectively support necrotic enteritis management. 100% natural OEO has various scientifically proven modes of action supporting necrotic enteritis management:

  • Direct anticoccidial effects – reducing the major predisposing factor
  • Gut healing and repair
  • Antibacterial effects
  • Immune support and anti-inflammatory responses
  • Antioxidant effects
  • Liver and kidney functions

Over 25 years of research has shown Orego-Stim supports broilers during necrotic enteritis challenge:

Improved feed efficiency

Improved liveability

Higher bodyweight gain

Improved EPEF

Improved lesion scores

Orego-Stim has been extensively researched to demonstrate it can help support animal performance during a necrotic enteritis challenge. Furthermore, Orego-Stim has been shown not to interfere with anticoccidial vaccine immunity, meaning existing anticoccidial management programmes can be continued.


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